Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis Running title: Cooperative oncogenes in leukemogenesis
نویسندگان
چکیده
Corresponding author: Takuro Nakamura, Department of Carcinogenesis, The Cancer Institute, Japanese Foundation for Cancer Research, 3-10-6 Ariake, Koto-ku, Tokyo 135-8550, Japan. Phone: +81-3-3570-0462, FAX: +81-3-3570-0463, e-mail: [email protected] This work was supported by KAKENHI (Grant-in-Aid for Scientific Research) on Priority Areas "Integrative Research Toward the Conquest of Cancer" from the Ministry of Education, Culture, Sports, Science and Technology of Japan.
منابع مشابه
Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis.
Cooperative activation of Meis1 and Hoxa9 perturbs myeloid differentiation and eventually leads myeloid progenitors to leukemia, yet it remains to be clarified what kinds of subsequent molecular processes are required for development of overt leukemia. To understand the molecular pathway in Hoxa9/Meis1-induced leukemogenesis, retroviral insertional mutagenesis was applied using retrovirus-media...
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تاریخ انتشار 2007